First time drinker

I had alcohol for the first time. I’m 30 years old, male, and around 400 pounds.

I drank half a bottle of Blackheart rum and it’s been 2 days and my body does not feel the same, I also take heavy medication for various illnesses including mental, could this be permanent?

The reason I never have drank before was because my Grandfather had a bad habit and I never did it until now when I hit my lowest point in life.