I’ve always understood this to be true such that if your first drink of the night is straight liquor, the liver and pancreas immediately start producing high levels of ADH to combat the alcohol. Conversely, if your first drink of the night is beer, it sets a precedent of a more mild response of ADH in your digestive track. It was my understanding that because of this, starting with beer would shock your digestive system later in the night if you moved up to a higher ABV drink.
Today I’ve learned that scientifically “beer before liquor never been sicker” is a myth, however, I am unable to find any studies that delve into the correlation between enzyme production and consuming beverages of varying alcohol concentration.
Can someone help me set the record straight?